|
|
 |
|
|
Etanercept
AltebrelTM,
is biosimilar product with the generic name of Etanercept. It uses for
treatment of several autoimmune diseases like Rheumatoid Arthritis, Plaque
Psoriasis, Psoriasis Arthritis, Spondylarthritis, Ankylosing Spondilities
and Juvenile Idiopathic.
Etanercept is a fusion protein consisting from a FC part of antibodies and
two TNF receptor. Etanercept is a homodimeric protein. Each monomer is
composed of an extra cellular receptor part which is banded to human TNFα
with Fc part of immunoglobulin IgG1.
Etanercept manufacturing is based on expression by a protein recombinant
technology using Chinese Hamster Ovary (CHO) cell. This molecule is composed
of 934 amino acids with weight of 150 KDa and acts as a TNFα Blocker. TNFα
is a kind of cytokines which is produced by monocytes and macrophages and
increases white cells flow to the site of inflammation. According to this
function beside some other related mechanisms, TNFα could increase
inflammation. So, Etanercept decreases inflammation responses through
inhibiting the mentioned TNFα mechanism which is completely effective in
treatment of autoimmune diseases.
This medicine is produced as prefilled syringe containing solution form with
two different dosages: 25 mg and 50 mg.
For more information visit us at www.altebrel.com
|
|
|
|
|
|
|
 |
Download prescription
information of AltebrelTM
|
|
|
|
